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KMID : 0191119970120020151
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Journal of Korean Medical Science
1997 Volume.12 No. 2 p.151 ~ p.156
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Guillain-Barre like syndrome associated with acute renal failure and thrombocytopenia following acute viral hepatitis A
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Lee DK
Do JK/Kim YJ
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Abstract
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We reported a 43-year-old woman who showed a Guillain-Barre like syndrome associated with acute renal
failure (ARF) and thrombocytopenia following acute viral hepatitis A(HA). The clinical feature was
acute progressive and of ascending symmetric paraparesis which developed 5 days after gastrointestinal
infection. Neurologic examination showed flaccid paraparesis, areflexia in all extremities and limitation
on the straight leg raising test. Laboratory examinations showed the evidences of ARF, thrombocytopenia
and HA. EMG findings suggested a polyradiculopathy. Renal biopsy showed the findings of acute interstitial
nephritis, acute tubular necrosis and IgA deposition nephropathy. She was treated by plasmapheresis and
platelet transfusion, then showed a rapid improvement, and has been well without further complication
after discharge.
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KEYWORD
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